This study investigates a new mediation model, in which individuals’ career choice goals are proposed to be influenced by the interplays of three influences including general self-efficacy, vocational interests, and person–job fit perceptions. Soon-to-be graduates of Hospitality and Tourism Management HTM) who just finalized their placement in the industry responded to self-completed questionnaires. They were 302 senior undergraduates from two institutes of higher education in tourism and hospitality on China’s Hainan Island. The four indirect causal paths within this mediation model include: a) general self-efficacy person–job fit choice goals, (b) general self-efficacy vocational interests choice goals, (c) general self-efficacy vocational interests person–job fit, and (d) vocational interests person–job fit choice goals. The results of structural equation modeling indicate that these four paths are all statistically significant and all the hypotheses regarding these paths therefore gain empirical support. The study’s findings as well as their implications are discussed within the context of self-efficacy theory, career development theory, and human resource development practices in the hospitality and tourism domain